Effects of three Commercial Mouth Rinses on the Cultured Fibroblasts: An in Vitro Study

نویسندگان

  • J Ghabanchi
  • A Moattari
  • R Darafshi
  • A Andisheh Tadbir
  • H Khorshidi
  • M Shakib
چکیده

STATEMENT OF PROBLEMS An ideal antimicrobial agent should have minimal cytotoxic effect to host cells. PURPOSE The aim of this study was to determine the cytotoxic effect of three commercial mouthwashes (Chlorhexidine, Persica and Irsha) on the cultured fibroblasts. MATERIAL AND METHODS For determining the cytotoxic effect of Irsha, Chlorhexidine and Persica, uninfected cells were grown in the absence and presence of various concentration (2,4,8,16,32,64,128) of these mouth washes for 1, 2, 3 and 4 days. RESULTS In this study, three mouth washes show cytotoxic effect on the cultured cells, at commercially available concentration and even diluted and Irsha was found to be the most toxic one. Cytotoxicity of three mouthwashes was reduced with decreasing concentration.

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عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2013